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Effect of a vegetable-oil emulsion on body composition; a 12-week study in overweight women on a meal replacement therapy after an initial weight loss: a randomized controlled trial.

European journal of nutrition
June 1, 2011
Johan Olsson et al. (4 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine if a vegetable-oil emulsion in a meal replacement could aid weight maintenance and reduce body fat mass after initial weight loss.

Results Summary

The study found no significant difference in weight loss between the vegetable-oil and control groups, but the vegetable-oil group showed a greater reduction in body fat mass (1.7% vs. 0.8%).

Population

Subjects who lost >5% body weight after a 6-week very low calorie diet.

Effective Dosage

Not specified

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
partial meal replacement diet containing a vegetable-oil emulsion (test)
decrease
weight
subjects with >5% body weight (BW) loss
1.0 ± 2.1 kg
A significant weight loss was observed
#1
partial meal replacement diet containing dairy fat (control)
decrease
weight
subjects with >5% body weight (BW) loss
1.3 ± 2.1 kg
A significant weight loss was observed
#2
partial meal replacement diet containing a vegetable-oil emulsion (test)
decrease
Body fat mass (BFM)
subjects with >5% body weight (BW) loss
--1.7%
decreased significantly
#3
partial meal replacement diet containing dairy fat (control)
decrease
Body fat mass (BFM)
subjects with >5% body weight (BW) loss
--0.8%
decreased
#4
Addition of a vegetable-oil emulsion to a meal replacement weight maintenance program after an initial weight loss using VLCD
decrease
Body fat mass (BFM)
subjects with >5% body weight (BW) loss
by 0.9%
was associated with decreased BFM
#5
Addition of a vegetable-oil emulsion to a meal replacement weight maintenance program after an initial weight loss using VLCD
no change
BW
subjects with >5% body weight (BW) loss
-
without any change
#6
Abstract

PURPOSE: The maintenance of an obtained lower weight level is often found to be difficult. The aim of this study was to determine weight maintenance after an initial weight loss by consumption of a meal replacement with a vegetable-oil emulsion associated with prolonged satiety. METHODS: After a 6-week weight loss period with very low calorie diet (VLCD), subjects with >5% body weight (BW) loss were randomized to a 12-week weight maintenance follow-up period, comparing a partial meal replacement diet containing a vegetable-oil emulsion (test) or dairy fat (control). Anthropometric data and safety variables were collected at baseline and after 4, 8 and 12 weeks. RESULTS: A significant weight loss was observed during the 12-week weight maintenance diet in the test and control group, respectively; 1.0 ± 2.1 kg (p < 0.05) versus 1.3 ± 2.1 kg (p < 0.05) with no significant difference between the groups. Body fat mass (BFM) decreased significantly (p < 0.05) in the test group (--1.7%) compared to the control group (--0.8%). CONCLUSIONS: Addition of a vegetable-oil emulsion to a meal replacement weight maintenance program after an initial weight loss using VLCD was associated with decreased BFM by 0.9% without any change in BW between the two groups.

Medical Subject Headings (MeSH)
AdolescentAdultBody CompositionBody Mass IndexBody WeightDiet, ReducingDouble-Blind MethodEmulsionsEnergy MetabolismFemaleFood, FormulatedHumansMiddle AgedOverweightPatient CompliancePlant OilsSatiety ResponseTime FactorsYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality80/10
Citation Metrics
Total Citations6
Citations/Year0.4
Relative Citation Ratio0.20
NIH Percentile10.1%
Research Impact Scores
APT Score0.25
Weight Score1.22
Normalized Score0.64
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