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The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: a 6-month randomized, controlled trial.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
January 1, 2011
Sabine M P Verschueren et al. (7 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether Whole-Body Vibration (WBV) training, combined with conventional or high-dose vitamin D supplementation, improves strength, muscle mass, and bone density in postmenopausal women.

Results Summary

WBV training did not provide additional improvements in muscle mass, strength, or hip bone mineral density compared to vitamin D supplementation alone. High-dose vitamin D increased serum levels but did not enhance musculoskeletal outcomes over conventional doses.

Population

Institutionalized elderly women aged over 70 years (mean age 79.6).

Effective Dosage

WBV training protocol not specified; vitamin D doses were 880 IU/day (conventional) and 1600 IU/day (high).

Duration

6 months

Interactions

None mentioned

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
whole-body vibration (WBV) training given a conventional or a high dose of daily vitamin D supplementation
increase
strength, muscle mass, and bone density
postmenopausal women
-
improving
#1
6 months of WBV and/or vitamin D supplementation
neutral
isometric and dynamic strength, leg muscle mass, and hip bone mineral density (BMD)
113 institutionalized elderly females aged over 70 years
-
determine the effects
#2
conventional and high-dose supplementation
increase
25-hydroxyvitamin D [25(OH)D] levels
-
-
the increase in
#3
6 months of treatment
increase
dynamic muscle strength, hip BMD, and vitamin D serum levels
all groups
-
improved significantly
#4
6 months of treatment
no change
isometric strength and muscle mass
all groups
-
did not change
#5
WBV program
no change
-
-
-
did not result in additional improvements
#6
high dose of 1600 IU of vitamin D
increase
serum vitamin D levels
-
-
did result in higher
#7
high dose of 1600 IU of vitamin D
no change
-
-
-
did not result in additional improvements
#8
WBV training protocol tested
no change
muscle mass, strength, and hip BMD
institutionalized women older than 70 years
-
is not more efficient in enhancing
#9
higher dose of 1600 IU of vitamin D
no change
-
this population
-
does not provide additional musculoskeletal benefit
#10
Abstract

Sarcopenia and osteoporosis represent a growing public health problem. We studied the potential benefit of whole-body vibration (WBV) training given a conventional or a high dose of daily vitamin D supplementation in improving strength, muscle mass, and bone density in postmenopausal women. In a 2 × 2 factorial-design trial, 113 institutionalized elderly females aged over 70 years (mean age 79.6 years) were randomly assigned either to a WBV or a no-training group, receiving either a conventional dose (880 IU/day) or a high dose (1600 IU/day) of vitamin D(3). The primary aim was to determine the effects of 6 months of WBV and/or vitamin D supplementation on isometric and dynamic strength, leg muscle mass, and hip bone mineral density (BMD). Additionally, the increase in 25-hydroxyvitamin D [25(OH)D] levels between conventional and high-dose supplementation was compared. After 6 months of treatment, dynamic muscle strength, hip BMD, and vitamin D serum levels improved significantly in all groups, whereas isometric strength and muscle mass did not change. When compared with no training, the WBV program did not result in additional improvements. When compared with 880 IU, a high dose of 1600 IU of vitamin D did result in higher serum vitamin D levels but did not result in additional improvements. In institutionalized women older than 70 years, the WBV training protocol tested is not more efficient in enhancing muscle mass, strength, and hip BMD compared with vitamin D supplementation. A higher dose of 1600 IU of vitamin D does not provide additional musculoskeletal benefit in this population compared with conventional doses.

Medical Subject Headings (MeSH)
AgedAged, 80 and overBone DensityDietary SupplementsFemaleHumansInstitutionalizationMuscle StrengthOrgan SizePatient ComplianceTreatment OutcomeVibrationVitamin D
Study Links
Quality Scores
SafetyNot Assessed
Efficacy30/10
Quality85/10
Citation Metrics
Total Citations88
Citations/Year6.3
Relative Citation Ratio3.41
NIH Percentile87.5%
Research Impact Scores
APT Score0.95
Weight Score1.54
Normalized Score0.49
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