Effect of a high-calcium energy-reduced diet on abdominal obesity and cardiometabolic risk factors in obese Brazilian subjects.
Study Goal
The researchers aimed to evaluate whether a high-calcium diet enhances the effects of energy restriction on abdominal obesity and cardiometabolic risk factors in obese subjects.
Results Summary
The study found that a high-calcium diet led to greater reductions in waist circumference, waist-to-hip ratio, and blood pressure compared to a low-calcium diet, alongside significant reductions in insulin levels. Both groups showed improvements in anthropometric and metabolic parameters under energy restriction.
Population
Obese Brazilian subjects of multiethnic origin, aged 22-55 years, with stable body weight and low calcium intake.
Effective Dosage
1200-1300 mg/day (supplemented with non-fat powdered milk, 60 g/day).
Duration
16 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
high-calcium diet (HCD) [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)] | decrease | insulin | Brazilian obese subjects of multiethnic origin | - | significantly reduced | #1 |
high-calcium diet (HCD) [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)] | decrease | waist circumference | Brazilian obese subjects of multiethnic origin | - | exhibited a greater reduction | #2 |
high-calcium diet (HCD) [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)] | decrease | waist-to-hip ratio | Brazilian obese subjects of multiethnic origin | - | exhibited a greater reduction | #3 |
high-calcium diet (HCD) [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)] | decrease | diastolic blood pressure | Brazilian obese subjects of multiethnic origin | - | exhibited a greater reduction | #4 |
high-calcium diet (HCD) [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)] | decrease | mean blood pressure | Brazilian obese subjects of multiethnic origin | - | exhibited a greater reduction | #5 |
energy-restricted diet (-800 kcal/day) | decrease | all anthropometric parameters | Brazilian obese subjects of multiethnic origin | - | a significant reduction was observed | #6 |
energy-restricted diet (-800 kcal/day) | decrease | metabolic variables (except for high-density lipoprotein cholesterol) | Brazilian obese subjects of multiethnic origin | - | a significant reduction was observed | #7 |
energy-restricted diet (-800 kcal/day) | decrease | blood pressure levels | Brazilian obese subjects of multiethnic origin | - | a significant reduction was observed | #8 |
BACKGROUND: Clinical trials designed to examine the effects of calcium supplementation on abdominal obesity have had ambiguous results. AIMS: This study aimed to evaluate, during energy restriction, the effects of a high-calcium diet (HCD) on measures of abdominal obesity and cardiometabolic risk factors in Brazilian obese subjects of multiethnic origin. METHODS: We conducted a randomised clinical trial. Fifty obese subjects of both sexes, aged 22-55 years, with stable body weight and a low calcium intake were randomised into the following outpatient dietary regimens: (i) a low-calcium diet (LCD; < 500 mg/day) or (ii) a HCD [1200-1300 mg/day, supplemented with non-fat powdered milk (60 g/day)]. Both groups followed an energy-restricted diet (-800 kcal/day) throughout the study (16 weeks). RESULTS: Thirty-nine participants completed the study. After 16 weeks of energy restriction, a significant reduction was observed in all anthropometric parameters, metabolic variables (except for high-density lipoprotein cholesterol) and blood pressure levels in both the groups. Insulin was significantly reduced only in the HCD group. Subjects on the HCD compared with those on the LCD exhibited a greater reduction in waist circumference (p = 0.002), waist-to-hip ratio (p = 0.0001), diastolic blood pressure (p = 0.04) and mean blood pressure (p = 0.03). CONCLUSIONS: Our study suggests that increased calcium intake may enhance the beneficial effects of energy restriction on abdominal obesity and blood pressure.