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A low-glycemic index diet in the treatment of pediatric obesity.

Archives of pediatrics & adolescent medicine
September 1, 2000
L E Spieth et al. (7 authors)
Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Human Study
Study Details

Study Goal

The researchers aimed to compare the effects of a low-glycemic index (GI) diet versus a standard reduced-fat diet on BMI and body weight in obese children.

Results Summary

The low-GI diet group showed significantly greater reductions in BMI (-1.53 kg/m²) and body weight (-2.03 kg) compared to the reduced-fat diet group. More patients in the low-GI group achieved a BMI reduction of at least 3 kg/m² (17.2% vs. 2.3%).

Population

107 obese but otherwise healthy children attending an outpatient pediatric obesity program.

Effective Dosage

Not specified

Duration

Mean follow-up of 4.3 months for the low-GI group and 4.2 months for the reduced-fat group.

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-glycemic index (GI) diet
decrease
body mass index (BMI)
obese but otherwise healthy children
-1.53 kg/m(2)
decreased more
#1
low-glycemic index (GI) diet
decrease
body weight
obese but otherwise healthy children
-2.03 kg
decreased more
#2
reduced-fat diet
decrease
body mass index (BMI)
obese but otherwise healthy children
-0.06 kg/m(2)
decreased
#3
reduced-fat diet
increase
body weight
obese but otherwise healthy children
+1.31 kg
increased
#4
low-glycemic index (GI) diet
decrease
BMI
patients in the low-GI group
at least 3 kg/m(2)
experienced a decrease
#5
Abstract

CONTEXT: Conventional dietary approaches for the treatment of obesity have generally yielded disappointing results. OBJECTIVE: To examine the effects of a low-glycemic index (GI) diet compared with a standard reduced-fat diet in the management of pediatric obesity. DESIGN: Retrospective cohort study of children attending an outpatient pediatric obesity program from September 1997 to December 1998. SETTING: Academic medical center. PARTICIPANTS: One hundred seven obese but otherwise healthy children. MAIN OUTCOME MEASURES: Changes in body mass index (BMI [calculated as weight in kilograms divided by the square of height in meters]) and body weight from first to last clinic visit. RESULTS: A total of 64 patients received the low glycemic index diet and 43 received the reduced-fat diet for 4.3 vs 4.2 months' mean duration of follow-up, with 3.3 vs 3.3 mean number of visits, respectively. Body mass index (-1.53 kg/m(2) [95% confidence interval, -1.94 to -1.12] vs -0.06 kg/m(2) [-0.56 to + 0. 44], P<.001) and body weight (-2.03 kg [95% confidence interval -3. 19 to -0.88] vs +1.31 kg [ -0.11 to + 2.72], P<.001) decreased more in the low-GI group compared with the reduced-fat group. In multivariate models, these differences remained significant (P<.01) after adjustment for age, sex, ethnicity, BMI or baseline weight, participation in behavioral modification sessions, and treatment duration. Significantly more patients in the low-GI group experienced a decrease in BMI of at least 3 kg/m(2) (11 kg/m(2) [17. 2%] vs. 1 kg/m(2) [2.3%], P =.03). CONCLUSIONS: A low-GI diet seems to be a promising alternative to standard dietary treatment for obesity in children. Long-term randomized controlled trials of a low-GI diet in the prevention and treatment of obesity are needed.

Medical Subject Headings (MeSH)
Blood GlucoseBody Mass IndexBody WeightChildDiet, Fat-RestrictedDiet, ReducingDietary CarbohydratesDietary FatsFemaleHumansInsulinMaleMultivariate AnalysisObesityRetrospective StudiesTreatment OutcomeWeight Loss
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality70/10
Citation Metrics
Total Citations180
Citations/Year7.2
Relative Citation Ratio4.92
NIH Percentile92.9%
Research Impact Scores
APT Score0.95
Weight Score0.69
Normalized Score0.68
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